Sunday, May 24, 2020

Animal Testing Should Be Banned From Our Society - 874 Words

Animal Rights Demand Protection My thesis is that animal testing should be banned from our society altogether. Animal rights advocates argue that testing is a subject that has been argued countless amount of times in medical journals, and it has shown that it is a waste of animal lives. Subsequently, processing of a single drug requires more than 50 trials and use of as many as 12,000 animals. Moreover, regardless of the ethical issues that derive from animal testing, the infliction of physical/psychological distress on animals are resource and time deterring. Furthermore, animal experimentation provides a source of limited knowledge of how certain chemicals would behave in a human body. (Humane Society International). Animal rights critics disagree. The National Association for Biomedical Research claims that every major medical advance is attributable to experiments on animals. Subsequently. approximately 70% of the American public supports the necessity of animal usage in biomedical research, since human testing is ethically unacceptable. Similarly, the 1997 USDA report, exposes the statistical data supporting the claim that most research (92%) was not painful to the animals involved. In the majority of cases (54%), the animals were â€Å"not directly exposed to painful procedures†.(National Association for Biomedical Research). In approximately 38% of cases, anesthesia or pain-relieving drugs were given in order to alleviate pain or distress. In about 8% of researchShow MoreRelatedSave Animals. Say No to Animal Testing!1390 Words   |  6 PagesArgumentative essay: Save animals. Say no to animal testing! Nowadays, it is a well-known fact that many companies test their products like cosmetics and medicines with animals before production to check their products ’safety and quality. A huge amount of animals are used in research purpose every year. Is it right for human beings to sacrifice millions of animals for testing purpose? Should animal testing be banned? Animal testing is a controversial issue and there is a heated debated about prosRead MoreAnimal Experimentation Should Be Banned1426 Words   |  6 Pagesjudged by the way its animals are treated.† - Mahatma Gandhi. These famous words still ring true in today’s society as we struggle to overcome the scientific experimentation on animals. Animals have acted as the archstone of human civilization since the dawn of man, from a source of food, to companionship. However, in the past century, we have been blurring the line between environmental entitlement and environmental rape. Every member of the human race inte racts and depends on animals, and we owe themRead MoreAnimal Testing Should Be Banned1263 Words   |  6 PagesAdult Education 19 May 2017 Animal Testing Should Be Banned Standard Number: 6.4.A Over 115 million animals are tested in laboratories throughout the United States each year. Typical animals included in these horrific tests include: cats, rats, dogs, rabbits, mice, monkeys, sheep, and birds. Researchers state that about 78,294 animals subjected to cosmetic and medicinal tests face severe pain (PETA, 2017). â€Å"Neither Federal nor state law prohibits the transfer of animals to laboratories; they onlyRead MoreThe Use Of Research On Cosmetics And Its Effects On Society1604 Words   |  7 PagesBlinded by Beauty On average, 26 million animals are used every year for the use of research on cosmetics. These tests should be banned for many obvious reasons such as it is clearly cruel and inhumane, they cost more than alternative methods, and they do not predict an accurate result due to the anatomical differences. Animals are being unfairly tortured and killed for research on ingredients that people are unknowingly using in their everyday lives. Here’s an important question to consider;Read MoreThe Morality Of Animal Testing And Its Effect On The Biomedical And Consumer World1698 Words   |  7 PagesThe Morality of Animal Testing and its Effect on the Biomedical and Consumer World Animal testing has been a controversial problem in today’s society and it affects people from all over the world1 not just animal activists or scientists. Most of the products and medicines used today have been tested on animals. These animals used in experiments have been thought to only benefit society but morally this hurts our society. This hurts our society because now animal testing has become a social normalityRead MoreThe Ethics Of Animal Testing1534 Words   |  7 PagesOver the last couple hundred years, our world has expanded beyond its horizons and the new equipment and advanced technology has allowed humans to succeed in many areas, but has also damaged the basic ethics and morals in some of us. Today on television, we see the over dramatized body spray commercials or a famous celebrity advertising their favorite shampoo and stating its claims, but what most do not know is that a couple or couple hundred, animals were killed to approve, by law, of that productR ead MoreHow Ethical Judgments Limit the Arts and Natural Sciences1349 Words   |  5 PagesOur ethical judgments will always limit us in gaining new knowledge in the arts and natural sciences. There are some methods that would work to uncover new information, but would go against ethical standards set by society such as animal and human testing. There is also the dilemma as to who should be able to access and view the information available. In art, a knowledge issue that arises is how do we determine what is appropriate for people to see? The innocent minds of children disappear when theyRead MoreAnimal Testing Should Be Banned848 Words   |  4 Pages As a society we have failed to notice, it’s everywhere. The animal testing footprint. Aeroguard, Chapstick, Michael Kors, Palmolive and Dettol: these common household brands all have the dark footprints of animal experimentation embedded into it. Each year over 6.5 million animals are brutally tested, killed or harmed in Australia and New Zealand, for many brands across the nation. You may think that Animal Testing has nothing to do with you but the real truth is, it does. It’s unavoidable toRead MoreAnimal Testing Should Be Banned855 Words   |  4 Pagesexperiments on animals. Animal experimentation has a lengthy and productive history in biological research, especially in biomedicine. Over ninety percent of studies used mice and rat to cure cancer and improve immune system for human beings (1). Since using animals in experiments is a practical way to cure many diseases, people overlooked the unethical action. However, animal testing should be forbidden because of its unsure benefits, morality and wastefulness. Opponents of banning animal testing argueRead MoreEssay on Cosmetics Testing on Animals, Is It Necessary?547 Words   |  3 PagesWhy should animals have to die, just for humans to have cosmetics? It is understandable if you want to cover up a scar on your face, but to just wear makeup because you think you need it, or because you feel like you cannot live without it, is ridiculous. Animals should not be dyeing for our insecurities on how we look, or on how society judges us. If society sees someone who is not Barbie or Ken perfect they judge us, so we put makeup on, it is not right for society to do that. Because of their

Wednesday, May 13, 2020

What is the Casimir Effect

Question: What is the Casimir Effect? Answer: The Casimir Effect is a result of quantum physics that seems to defy the logic of the everyday world. In this case, it results in a vacuum energy from empty space actually exerting a force on physical objects. While this may seem bizarre, the fact of the matter is that the Casimir Effect has been experimentally verified many times over and provides some useful applications in some areas of nanotechnology. How the Casimir Effect Works The most basic description of the Casimir Effect includes a situation where you have two uncharged metallic plates near each other, with a vacuum between them. We normally think that theres nothing between the plates (and therefore no force), but it turns out that when the situation is analyzed using quantum electrodynamics, something unexpected happens. The virtual particles created within the vacuum create virtual photons which interact with the uncharged metal plates. As a result, if the plates are extremely close together (less than a micron) then this will become the dominant force. The force drops off quickly the further apart the place is. Still, this effect has been measured to within about 15% of the value predicted by the theory itself, making it clear that the Casimir effect is quite real. History and Discovery of the Casimir Effect Two Dutch physicists working at the Philips Research Lab in 1948, Hendrik B. G. Casimir and Dirk Polder, suggested the effect while working on fluid properties, such as why mayonnaise flows so slowly ... which just goes to show that you never know where a major insight will come from. Dynamic Casimir Effect A variant of the Casimir Effect is the dynamic Casimir effect. In this case, one of the plates moves and causes the accumulation of photons within the region between the plates. These plates are mirrored, so that the photons continue to accumulate between them. This effect was experimentally verified in May 2011 (as reported in Scientific American and Technology Review). It is demonstrated (without much fanfare ... or audio) on this YouTube video. Potential Applications One potential application would be to apply the dynamic Casimir effect as a means of creating a propulsion engine for a spacecraft, which would theoretically propel the ship by using the energy from the vacuum. This is a highly ambitious application of the effect, but it appears to be one suggested to a bit of fanfare by an Egyptian teenager, Aisha Mustafa, who has patented the invention. (This alone doesnt mean much, of course, since theres even a patent on a time machine, as described in Dr. Ronald Malletts non-fiction book Time Traveler. A lot of work must still be done to see if this is feasible or if it is just another fancy and failed attempt at a perpetual motion machine, but here are a handful of articles focusing on the initial announcement (and Ill add more as I hear about any progress): OnIslam.com - Egyptian Student Invents New Propulsion Method, May 16, 2012Fast Company - Mustafas Space Drive: An Egyptian Students Quantum Physics Invention, May 21, 2012Crazy Engineers - New Propulsion Method Using Dynamic Casimir Effect Invented by Egyptian Student, May 27, 2012Gizmodo - Egyptian Teenager Invents New Space Propulsion System Based on Quantum Mechanics, May 29, 2012 There have also been various suggestions that the bizarre behavior of the Casimir effect could have applications in nanotechnology - that is, in very small devices built at atomic sizes. Another suggestion put forth has been tiny Casimir oscillators which would be a tiny oscillator that could be used in various nanomechanical systems. This particular hypothetical application is explained in greater and more technical detail in the 1995 Journal of Microelectromechanical Systems article The Anharmonic Casimir Oscillator (ACO)-- The Casimir Effect in a Model Microelectromechanical System.

Wednesday, May 6, 2020

What’s Gone Wrong with the Third Italy Free Essays

string(137) " the harsh reality of such a business type: poor working conditions and safety conditions, longer work hours and low paid working hours\." Msc BUSINESS ADMINISTRATION INTERNATIONAL BUSINESS CONTENT Introduction p. 3 Early glitches of the SMEs within the industrial districts p. 5 Analysis of two of the regional clusters at stake p. We will write a custom essay sample on What’s Gone Wrong with the Third Italy or any similar topic only for you Order Now 6 What went wrong? p. 7 Concluding remarks p. 9 References p. 10 Introduction The purpose of this paper is to determine to which extent the economic areas known as ’Third Italy’ have not managed to achieve the well-desired status. The local development model has been presented as the perfect small-scale flexible capitalist type that has adopted a post-Fordist mode of production (Grancelli, 2007). The economic cluster referred to as Third Italy, was founded in the post-war period (1950s and 1960s) when the global economy was going through hard times of recovery. In the north-east part of Italy a new type of firms was developed. The question may be put why didn’t the other two important industrialized districts known as First Italy (the industrial heartland of the North) and the Second Italy (the backward South) have become the regions of wealth and economic growth. The answer lies primarily in the cultural values: the local culture of entrepreneurship and cooperation (Boschma, 1998) that to some extent doesn’t apply for other Italian regions. The following figure displays accurately the industrial zone of Italy: According to Bagnasco (1977) from a economic point of view Italy was divided into the ’Three Italies’: the North-west, the big companies, was tagged as ’central economy’, the shallow regions of the South seen as ’marginal economy’ and the central-North-eastern regions- known as Third Italy- haracterized by the presence of small firms that are defined as ’peripheral economy’. Nonetheless, the way in which the Third Italy region was defined didn’t hide the real facts; when compared to the North-west typology, productivity per worker and work unit-costs were sensibly lower. But this didn’t disable the central-north-east cluster to have a significant development pr ocess that is confirmed by: a reduction of agricultural employees, an increase in manufacturing workers, growth in resident population, and an upward trend in Italy’s industrial national product (Bianchi, 1998). The â€Å"Third Italy† region, also referred to as Emilia-Romagna, forms a north-eastern group of counties that propelled themselves to a position of prosperity between the relatively wealthy north-western triangle of Italy and the relatively impoverished Mezzagiorno region south of Rome (Walcott, 2007). Localized production centres utilize export-oriented niche specializations to create place-based economies supporting local firms. Related residents supply both low labour costs and endogenously accumulated capital. Light industrial products include foods, clothing, shoes, furniture, and metal work for a craft-based market. Building on a textiles and leather goods specialization, that demands rapid responses to a notoriously fickle fashion market, familial and other locally forged trust-based ties enabled local star â€Å"Benetton† to become an international fashion retail chain. Knowledge of the local market was so finely tuned that offerings were famously differentiated even within the same city (Walcott, 2007). External economies of place propelled tightly organized local regions to maximize returns based on clearly defined sectoral specialization. In one example clearly defying physical topography, Silicon Valley imitators sprang up around the globe as hopeful high technology havens. A real estate set-aside does not an industrial district make, however (Walcott, 2007). Early glitches of the SMEs within the industrial districts In the early 1990s the one of the menacing forces against the Italian industrial clusters was the post-industrial transition. The internationalization of the economy endangers the developing process of small-scale firms. One good argument is the external market that provides expanded multinational, multi-product, multi-market companies (Holland, 1987). Even if the European Union is trying to help out these businesses by adopting policies and programmes the structural problems are not accurately aimed (Dastoli and Vilella, 1992: 179). Firms part of the Italian industrial district were running short of breath confirming that the market by its self regulation has launched an attack to the ’small is beautiful’ saying. Innovation plays a key part in the life of small and medium enterprises (SMEs) from the industrial clusters. It is noticed a decline in the importance of factors sources of external economies) that empowered the initial outset of the firms. The long used external sources were starting to lose grip in the face of the needed environmental efficiency (Bianchi, 1998). The changes that had to be performed weren’t a walk in the park. According to Bianchi (1990): the local entrepreneurs’ social culture and the past history successes disable the belief of urgent innovation investment. Also, economic barriers have prohibited small firms to access the large scale research and development, marketing and etc. (Regini and Sabel, 1989). Furthermore, two additional problems sprung up from the innovation process that need to be taken into consideration: ’product innovation’ in those zone of production with a highly design content that subtracts the formal innovation side rather than the technological innovation, because the first one includes creativity, imagination and taste, factors that are not easily obtained in business-set like this. The other difficulty is process innovation meaning that adopting a higher technological labour focused system would both increase productivity and decrease costs (Bianchi, 1998). Hadjimicalis (Hadjimicalis, 2006) introduces a set of arguments that could nevertheless be the real ones behind Third Italy’s downturn. ’The lack of attention to the role of state’ implies the obsolete focus on different direct and indirect protectionist measures and regulations as in the work of radicals Stoper (1997) and Scott (1988). The most important protectionist measures as the Multi-Fibre Agreement that went in favour for Italy’s blooming manufacturing industries. The regulatory decisions have protected Italy along with other countries from ’unlimited competition’ in garments and textiles from the menacing low waged countries in the Eastern part of the world. Another governmental intervention was the fiscal regulation which consisted the hedging the exchange rates for the lira due to the devaluations throughout the 20th century and one of them when Euro currency was adopted in 2001. An interesting fact is that all those authors that supported the theories behind Third Italy industrial clusters as (Asheim 1999, Becattini 1990, Cooke 1988) haven’t seen the harsh reality of such a business type: poor working conditions and safety conditions, longer work hours and low paid working hours. You read "What’s Gone Wrong with the Third Italy" in category "Papers" All the other specific characteristics of the small-scale enterprises from the region as: flexibility, innovation and embbededness of small firms (Hadjimichalis, 2006). Another term that was used to explain the success of Italian IDs is ’social capital’. It is the theoretical concept that has been used by various authors. A good perspective is seen through the lenses of Hadjimichalis: ’From individuals to communities, from firms to families, from cooperation to competition, from working conditions to unions, from trust and reciprocity to corruption and from the success to the failure of a place, all are called social capital’, this explaining clearly the real trend of firms within the Italian industrial clusters. Analysis of two of the regional clusters at stake The most remarkable evolution oscillations can be outlined in Emilia-Romagna and Veneto provinces, where ’industrialisation without breaks’ (Fua,1983) was followed by a third party strategy ’without breaks’ which means that the regions have gained the prestige of stability organisms within the frontier of national development. The Piedmont and Lombardy are also good examples for the comparative advantage of their early launch and the lasting predominance of their industries provided the solid foundations for a strong post-industrial transition (Bianchi, 1998). Tuscany, on the other hand, has badly faced up to the need to restructure during the 1980s. Its historical memory describes best the anti-industrial attitude of its ruling class. Differences between the two provinces within the Third Italy are clear. The Emilia-Romagna’s type of industrial development is seen as unique and deeply rooted in the region’s culture and entrepreneurial activity (Heidenreich, 1996) and when compared to Tuscany’s inability to cope with a model of development that seems inapplicable to the case. Table 1 underlines the two differences in between the two regions described above. What went wrong? The industrial district of Third Italy (IDs) have suffered severe changes during the early 1990s because of the demand fall for Made in Italy products along with the emergence of new lower waged Eastern Europe companies and developing countries (Grancelli,2006). The active devaluation of the lira due to the euro introduction had a significant impact on the upward trend of Italian exports. The small-scale enterprises that have set a foothold into the creation of the so-called Third Italy region, were basically family businesses which put all into a network bowl had formed the leading industrial area of Italy and a model to follow on by the emerging countries. Following the same idea it could be said that the demographic decline has started a process of ’social construction of the market’ (Bagnasco ;amp; Triglia 1984; Dei Ottati 1995; Provasi 2002). The financial global crisis has put its fingerprint on the actual Italian industrial districts, but those enterprises that could jump incremental innovation and ensure a competitive position globally had somewhat survived the impact (Whitford, 2001). The latter example of firms shows that they have created vertically integrated organizational blueprints, and made foreign direct investments in contrast to the swept out firms that have just relocated part of their production (Grancelli, 2006) to low pay working force or to attract foreign workers in the home production facilities. According to Hadjimichailis (2006) : The erosion of the Italian industrial clusters was made through: ’ Relocation of production in Eastern Europe in search of low labour costs’ and this gave birth to: a severe increase in unemployment percentages and adding the hiring of immigrant workers within the Italian borders. Hadjimichailis (2006) also introduces the ’bloody Taylorism’ term which is used in relation to the destination markets of the Italian entrepeneurs, Eastern Europe countries. This is used in connection to the SMEs of Veneto which were thought to re-establish Fordist factories due to delocalization processes. One example is the relocated production quotas abroad which ranged from 23% to 45% that resulted in a decrease of 28% of employment, 38% of production units in the region. This being said, the following concluding remarks could be made: ’Fordism is not only alive and well at the global scale, but it also returns as a solution to Italian firms’ from the industrial clusters, which were the models of flexibility and industrial district mythology (Hadjimichailis, 2006 : 95). The eastern slide of some of the sub-contractors from the Third Italy confirms the ideology that coordination between subsidiaries abroad and the parent company could not be only made through tacit knowledge of skilled workers and technicians remains an important factor even in a globally set value chain (Biggero, 2006). Those actors that have relocated their business into the Eastern part of Europe, Romania or other Balkan countries are seen as ’extroverted actors’ that also maintained relations within the home country district (Tappy, 2005). An important technological disequilibrium was introduced in the late 1960s – plastic materials for ski boots – by the lively research of external knowledge through some of leading firms. Another challenge of the north-eastern industrial clusters is the superior technological level of the products and putting a foot in the door of appealing mergers and acquisitions. Old, traditional and family driven businesses that are identified within the Third Italy areas need to see the ever changing strategy patterns as to going from a production to design phase which could attract cost diminishing (Cooke, 1998). It must not be neglected the power created by the tight bonded social network that has nurtured its roots for more than 50 years and before de ’90s has raised economic analysts’ eye browses throughout the world. Concluding remarks In order to survive, Italian industrial districts need to be fulfilling the following two conditions: their social and geographical division of labour remains globally competitive as compared to similar areas, sectors and other forms of industrial production, and their internal system of social reproduction remains unchallenged. Hadjimichalis, 2006) Mergers and acquisitions with famous brand names could be live threats for the small business embedded firms from the industrial zones of Italy. The power of Fordism has not dawned; in fact there is an increase of business deployment using this theory mainly in the Eastern countries. De-localization breaks the mesmerizing effect of small-scale flexible companies and builds up the multinational comp any picture having vertical integrated characteristics. The presence of a huge wave of non-EU immigrants also changes the parameters of the Third Italy’s rather stable local social structure, with a cap on immigrations that could preserve craft traditions and the reproduction of skills. Even though ’Third Italy’ concept is turning ethereal, the back stage offers the resources, specific capabilities and core competencies developed throughout the years by the district firms to achieve competitive advantage in their markets but also to allow their sub-parts within the industrial system (Schiavone, 2004). As theories claim Third Italy revolves around the social capital theories that also could be a driver for economic performance (Granato et al. , 1996). In addition to too little social capital, too much social capital could have a negative impact on economic performance (Boschma and Lambooy, 2002). Finally, it could be assumed that the process of rethinking and reorienting of Third Italy’s entrepreneurial and family based firms has done a significant change to whole industrial aggregate. References Asheim B. (1999), â€Å" Interactive learning and localized knowledge in globalising learning economies†. Geojournal 49(4):345–352 Bagnasco, A. ,Trigilia, C. (eds) (1984), â€Å" Societa e politica nelle aree di piccola impresa: Il caso di Bassano, Venezia: Arsenale Editrice. agnasco†, A. ,Trigilia, C. (eds) (1984), Societa e politica nelle aree di piccola impresa: Il caso di Bassano, Venezia: Arsenale Editrice. Becattini G. , (1990) â€Å"The Marchallian industrial district as a socio-economic notion. In F Pyke, G Becattini and W Sengerberger (eds) Industrial Districts and the Interfirm Co-operation in Italy† (pp 132–142). Geneva: ILO Bianchi, G. (1998), â€Å"Requiem for the Third Italy? Rise and fall of a too successful concept†, Entrepeneurship;amp; Regional Development, 10 (1998), 93-116. Biggero, L. (2006), â€Å"Industrial and knowledge delocation strategies under the challenges of globalization and digitalization: the move of small and medium enterprises among territorial systems† , Entrepreneurship and Regional Development, 18: 443-471 Boschma, R. A. , and Lambooy, J. G. 2002. â€Å" Knowledge, market structure and economic co-ordination: the dynamics of industrial districts. Growth and Change† 33 (3): 291-311. Boschma, Ron A. , Kloosterman R. C. (1998), â€Å"Learning from Clusters: A Critical Assessment†,  © 2005 Springer. Printed in the Netherlands. 139–168. Cooke P. , (1988) â€Å" Flexible integration, scope economies and strategic alliances: Social and spatial mediation†. Society and Space 6:281–300 Cooke P. , Morgan, K. (1998), â€Å" The Associational Economy†, Oxford: O. U. P. Dastoli, P. V. and Viclla, G. 1992â€Å" La Nuova Europa. Dalla Comunita all’ Unione (Bologna: II Mulino) † Dei Ottati, G. (1995), â€Å"Tra mercato e comunita: Aspetti concettuali e ricerche empiriche sul distretto industriale†, Milano: F. Angeli. Fua, G. and C. Zacchia (1983) (a cura di), â€Å" Industrializzazione senza fratture, Bologna: Il Mulino†. Granato, J. , Inglehart, R. , and Leblang, D. (1996). â€Å"The effect of cultural values on economic development. Theory, hypotheses, and some empirical testsâ€Å". American Journal of Political Sciences 40 (3): 607-631 Grancelli, B. , Chiesi A. M. (2006), â€Å"Elites-in-the-making and their organizational behaviour: Cases in Russia and the Balkans†, in B. Dallago (ed. ), Transformation and European Integration. The Local Dimension, London: Palgrave. Holland, S. 1987), â€Å"The Market Economy, From Micro- To Meso-Economics† ( London: Weidenfeld ;amp; Nicholson). Hadjimichalis, C. (2006), â€Å"The End of Third Italy as we knew it ? â€Å", Editorial Board of Antipode. Published by Blackwell Publishing, 9600 Garsington Road, Oxford OX4 2DQ, UK and 350 Main Street, Malden, MA 02148, USA Heidenreich, M. 1996 â€Å"Beyond flexible specialization : the rearrangement of regional production orders in Emilia-Romagna and Baden-Wurttemberg†, European Planning Studies, 4: 401-420 Makdisi S. , Casarino C. , Karl R. E. , â€Å"Marxism Beyond Marxism† Routledge, London, 1996, pg. 155 Provasi, G. (2002) (Ed. ), â€Å"Le istituzioni dello sviluppo, Roma: Donzelli Regini, M. and Sabel†, C. 1989 Strategic di riaggiustamento industriale (Bologna: II Mulino). Schiavone ,F. , Dezi L. (2004), â€Å"Managerial Styles within an Italian Industrial District:Two different successful storiesâ€Å" Scott A and Storper M (1988) â€Å"The geographical foundations and social regulation offlexible production complexes†. In J Wolch and M Dear (eds) The Power of Geography (pp 21–40). London: Allen and Unwin Storper M (1997) â€Å"The Regional World: Territorial Development in a Global Economy†. New York: Guilford Tappi, D. 2005) â€Å"Cluster, adaptation and extroversion. A cognitive and entrepreneurial analysis of the Marche music cluster†, European Urban and Regional Studies, 12/3: 289- 307. Walcott, Susan M. (2007) â€Å"Wenzhou and the Third Italy: Entrepreneurial Model Regions†, Journal of Asia-Pacific Business, 8: 3, 23 — 35 Wh itford, J. (2001), â€Å"The decline of a model? Challenge and response in the Italian industrial districts†, Economy and Society, 30/1: 38-65. ——————————————– [ 1 ]. Theory that appeared after the ‘Fordism’ period in which a mass consumer was targeted, products standardized and costs lowered. Post-Fordism’ is characterized by ‘flexible specialization’ based on dense networks of flexible, strongly related, mostly small and medium-sized firms in mainly craft-based industries that are concentrated in specialised industrial districts(Boschma,1998). [ 2 ]. Copyright 2010 privileges set. [ 3 ]. SME-small and medium enterprises [ 4 ]. Putnam’s work on Italy (1993), Porter’s on clusters (1998) [ 5 ]. (Casarino, 1996) – After the Industrial Revolution, a mechanical engineer called Frederick W. Taylor proposed a new way to organ ize factories and shop floors with what he called the â€Å"Scientific Management†. How to cite What’s Gone Wrong with the Third Italy, Papers

Sunday, May 3, 2020

Errors in DNA Replication Essay Sample free essay sample

Deoxyribonucleic acid reproduction is a biological procedure that occurs in all life beings and transcripts their Deoxyribonucleic acid ; it is the footing for biological heritage. The procedure starts when one double-stranded DNA molecule produces two indistinguishable transcripts of the molecule. The cell rhythm ( mitosis ) besides pertains to the DNA replication/reproduction procedure. The cell rhythm includes interphase. prophase. metaphase. anaphase. and telophase. Each strand of the original double-stranded DNA molecule serves as templet for the production of the complementary strand. a procedure referred to as semi-conservative reproduction. Cellular proofreading and error-checking mechanisms guarantee near perfect fidelity for DNA reproduction. While most DNA replicates with reasonably high fidelity. errors do go on. with polymerase enzymes sometimes infixing the incorrect base or excessively many or excessively few bases into a sequence. Fortunately. most of these errors are fixed through assorted DNA fix processes. But some reproduction mistakes make it past these mechanisms. therefore going lasting mutants. We will write a custom essay sample on Errors in DNA Replication Essay Sample or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page These altered nucleotide sequences can so be passed down from one cellular coevals to the following. and if they occur in cells that give rise to gametes. they can even be transmitted to subsequent organismic coevalss. Furthermore. when the cistrons for the DNA fix enzymes themselves become mutated. errors begin roll uping at a much higher rate. In eucaryotes. such mutants can take to malignant neoplastic disease. ERROR CORRECTION: Deoxyribonucleic acid reproduction mistakes include:A ) Adding bases ( more than that are supposed to be added ) . B ) Removing bases ( from topographic points they are supposed to be in ) . C ) Puting bases in incorrect topographic points. DNA polymerase enzymes are surprisingly peculiar with regard to their pick of bases during DNA synthesis. guaranting that the bases added to a turning strand are right paired with their complements on the templet strand ( i. e. . A’s with T’s. and C’s with G’s ) . However. these enzymes do do errors at a rate of about 1 per every 100. 000 bases. n worlds. with our 6 billion base braces in each diploid cell. that would amount to approximately 120. 000 errors every clip a cell divides. Fortunately. cells have evolved extremely sophisticated agencies of repairing most. but non all. of those errors. Some of the errors are corrected instantly during reproduction through a procedure known as proofreading. and some are corrected after reproduction in a procedure called mismatch fix. When an wrong base is added to the turning strand. reproduction is stalled by the fact that the nucleotide’s exposed 3?-OH group is in the â€Å"wrong† place. During proofreading. DNA polymerase enzymes acknowledge this and replace the falsely inserted nucleotide so that reproduction can go on. Proofreading holes about 99 % of these types of mistakes. but that’s still non good plenty for normal cell operation. After reproduction. mismatch fix reduces the concluding mistake rate even further. Falsely paired bases cause malformations in the secondary construction of the concluding Deoxyribonucleic acid molecule. During mismatch fix. enzymes acknowledge and repair these malformations by taking the falsely paired nucleotide and replacing it with the right base. DNA fix. include. basal deletion fix. nucleotide deletion fix. double-strand DNA interruption fix. and mismatch fix ( MMR ) .